It is 1932 when loyal, devoted Nurse Eunice Evers is invited to work with Dr. Brodus and Dr. Douglas on a federally funded program to treat syphilis patients in Alabama. Free treatment is offered to those who test positive for the disease included Caleb Humphries and Willie Johnson. But when the government withdraws its funding, money is offered for what will become known as "The Tuskegee Experiment", a study of the effects of syphilis on patients who don't receive treatment. Now the men must be led to believe they are being cared for, when in fact they are being denied the medicine that could cure them. Miss Evers is faced with a terrible dilemma-to abandon the experiment and tell her patients, or to remain silent and offer only comfort. It is a life or death decision that will dictate the course of not only her life, but the lives of all of Miss Evers' Boys.